Fluorescent Chemosensors and Imaging Agents


主讲人:Professor Tony D James,University of Bath




主讲人介绍:Tony D James is a professor at the University of Bath and Fellow of the Royal  Society of Chemistry where he holds a prestigious Royal Society Wolfson Research  Merit Award. (2017-2022). BSc 1986 (University of East Anglia), PhD 1991  (University of Victoria), Postdoctoral Research Fellow 1991-95 (Seiji. Shinkai)  and Royal Society Research Fellow from 1995 to 2000 (University of Birmingham).  He has been a visiting professor at Tsukuba, Osaka, Kyushu and Sophia  Universities, an AMADEus invited professor at the University of Bordeaux and is  a guest Professor at East China University of Science and Technology, Xiamen  University, Shandong Normal University, Nanjing University, Shaanxi University  of Science and Technology, Changzhou University, Zhejiang University, Qufu  Normal University and Hai-Tian (Sea-Sky) Scholar at Dalian University of  Technology. He was awarded the Daiwa-Adrian Prize (2013), the Inaugural CASE  Prize (2015) and MSMLG Czarnik Award (2018). He has over 305 publications,  including two books, 9 book chapters and 294 papers in international peer  reviewed journals. He is also the named inventor on 25 international patents. He  has delivered 241 invited lectures within the UK and internationally. Citation  statistics indicate that one of his publications has been cited over 700 times,  two over 500, five over 300, seventeen over 200 times, thirty-three over 100,  and 82 over 50, with a total of >15,388 citations at a frequency of >50  citations per article. He has an h-index of 65 (November 2019 ORCID  0000-0002-4095-2191).

内容介绍:The ability to monitor analytes within physiological, environmental and  industrial scenarios is of prime importance. Given that recognition events occur  on a molecular level, gathering and processing the information poses a  fundamental challenge. Therefore, robust chemical molecular sensors  “chemosensors” with the capacity to detect chosen molecules selectively and  signal this presence continue to attract considerable attention. This  presentation will concentrate on fluorescent probes developed using boronic  acids for diols, anions and reactive oxygen/nitrogen species (ROS/RNS). The aim  of the research is to mimic nature’s level of sophistication in designing and  producing chemosensors capable of determining the concentration (and location)  of a target species including: saccharides, glycated proteins, anions and  reactive oxygen/nitrogen species (ROS/RNS) in any medium.